Future-Oriented Conditioning

NAD+ Nasal Liposome Kit

A new, needle-free NAD+ routine.

NAD+

What is NAD+?

NAD+ (Nicotinamide Adenine Dinucleotide) is a central coenzyme found in all cells that supports mitochondrial function, which produces energy (ATP).

It is also considered extremely important for maintaining health and preserving youthfulness because it activates the “sirtuin genes” (longevity genes) involved in DNA repair and cellular anti-aging. However, NAD+ levels in the body decline with age, and it is said that they drop to about half of their peak levels around the age of 45.

Purpose and Features of This Treatment

This treatment aims to efficiently replenish NAD+ levels that have declined with age, with the goal of improving brain function, promoting anti-aging, and restoring mitochondrial function.

Manufactured in Japan

Typically, when NAD+ is administered orally (as a supplement) or via IV drip, it breaks down before being taken up by cells, making it extremely difficult to deliver it directly to the brain (due to the blood-brain barrier). Furthermore, since intracellular resynthesis requires an enzyme called NAMPT, which decreases with age, the effectiveness varies from person to person.

This treatment overcomes these challenges through the following two technical innovations
As a result, it directly boosts the NAD+ pool in the brain, promising high efficacy.

Intranasal Administration

By traveling through the olfactory and trigeminal nerve pathways in the nasal mucosa, the drug bypasses the blood-brain barrier and reaches the brain (central nervous system) directly.

Liposomal Formulation

By encapsulating NAD+ in nanoparticles composed of the same components as cell membranes (lipid bilayers), it is protected from degradation by enzymes in the body and can pass through the cell membrane to reach the interior of the cell (mitochondria) directly.

Convenient and Easy-to-Maintain Nasal Sprays

A nasal spray is a method of administering medication by spraying it into the nasal cavity.
Because the nasal mucosa has a rich blood supply, certain ingredients can be absorbed without passing through the digestive tract. Additionally, since this method is non-invasive—unlike injections—its use has been expanding across various fields in recent years. Furthermore, a key advantage of intranasal administration is that it is less susceptible to the first-pass effect (metabolism in the liver) compared to oral intake.

  • It is easier to maintain than injections or IV drips, making it simple for even busy individuals to incorporate into their daily lives.
  • Since it does not use needles, it is a popular choice for those who dislike injections.
  • Liposome technology encapsulates the active ingredients, ensuring stability and a comfortable user experience.

Recommended for:

  • Those who can’t shake off chronic fatigue
  • hose in their 40s and older who want to strengthen their inner care for health and beauty
  • Those who want to incorporate daily care into their routine or prefer to do everything at home
  • Those who want to prevent cognitive decline and other brain function deterioration

Expected Effects

The following effects are expected when this product is sprayed into and absorbed by the nasal cavity.

  • Improved Brain Function

    Improved cognitive function, concentration, and memory.

  • Neuroprotection

    Inhibition of neuroinflammation and improvement of mitochondrial function, leading to the suppression of progression and improvement of symptoms in neurological diseases such as Alzheimer’s and Parkinson’s.

  • Improved Physical Functioning

    Reduced fatigue and increased energy levels.

  • Anti-Aging & Metabolic Support

    Delays the aging process, prevents and improves metabolic-related diseases, and improves mood.

Treatment Method (Usage and Dosage)

Please administer the nasal spray yourself, following your doctor’s instructions.

  • IndicationsAdults
  • UsageSpray 1 to 2 pumps into each nostril.
    Tilt your head back slightly while doing so.
  • Dosage2–3 times daily. Use one bottle within 14 days; store in the refrigerator.

Precautions

Before undergoing this treatment, you must fully understand the following risks.

  • This is an investigational treatment:Intranasal liposomal NAD+ is a groundbreaking treatment based on theoretical and anatomical evidence, but it is currently in the research phase. Large-scale clinical trial data in humans is limited, and long-term safety and definitive efficacy have not been fully established.
  • Safety and Ingredients:The ingredients of the nasal spray (NAD+ itself, preservatives, etc.) and its pH may affect absorption and stability in the nasal mucosa.
  • Side Effects:Transient nasal irritation, dryness, and mild headaches may occur. If you experience severe pain, persistent bleeding, or allergic symptoms (such as a rash or difficulty breathing), stop using the product immediately and contact our clinic.
  • Unapproved Drug / Self-Pay Treatment:Since this medication is not approved under Japan’s Pharmaceutical Affairs Law, the full cost of treatment must be borne by the patient (self-pay). Additionally, it is not covered by the adverse reaction relief system.
  • Technical Difficulty and Cost:Liposomal NAD+ is technically very difficult to produce, and due to high manufacturing costs, the drug price is set at a high level.

Price（include tax）

Nasal Liposome NAD+ Kit
1 bottle (10–14 days)¥55,000
1-month set (3 bottles)¥148,500