{"id":1575,"date":"2026-01-02T19:36:06","date_gmt":"2026-01-02T10:36:06","guid":{"rendered":"https:\/\/www.yamate.clinic\/en\/?page_id=1575"},"modified":"2026-04-21T17:05:59","modified_gmt":"2026-04-21T08:05:59","slug":"external","status":"publish","type":"page","link":"https:\/\/www.yamate.clinic\/en\/external\/","title":{"rendered":"External Medications"},"content":{"rendered":"<p><main id=\"content\" role=\"main\"><\/p>\n<section class=\"hero-area bg-img-center content-space-1\">\n<div class=\"container-xxl pt-3 pt-lg-5 px-0\">\n<div class=\"d-flex bg-img-center\" style=\"background-image: url(https:\/\/yamate.clinic\/wp-content\/themes\/yycen\/assets\/img\/bg-img\/bg-window-sunlight.jpg);\">\n<div\n            class=\"container d-flex justify-content-end flex-column min-vh-35 min-vh-lg-50 content-space-1 content-space-lg-b-3\"><\/p>\n<div class=\"w-lg-65\">\n<h1 class=\"display-5\">External Medications<\/h1>\n<\/div>\n<nav aria-label=\"breadcrumb\">\n<ol class=\"breadcrumb\">\n<li class=\"breadcrumb-item\"><a href=\"https:\/\/yamate.clinic\/en\">Home<\/a><\/li>\n<li class=\"breadcrumb-item active\" aria-current=\"page\">External Medicine<\/li>\n<\/ol>\n<\/nav>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"service-area content-space-t-1 content-space-b-2\">\n<div class=\"container\">\n<div class=\"row mb-5\">\n<div class=\"col-12\">\n<div class=\"item-box mb-5 wow fadeInUp\" id=\"01\" data-wow-delay=\"0.1s\">\n<h3>NAD+ Nasal Liposome Kit<\/h3>\n<div class=\"py-2\">\n<span class=\"item-2\">Cognitive Function<\/span><span class=\"item-2\">Focus<\/span><span class=\"item-2\">Memory<\/span><span class=\"item-2\">Neuroprotection<\/span><span class=\"item-2\">Fatigue Reduction<\/span><span class=\"item-2\">Energy Boost<\/span><span class=\"item-2\">Anti-Aging<\/span><span class=\"item-2\">Metabolism<\/span><\/div>\n<div class=\"card mb-3\">\n<div class=\"card-body\">\n<div class=\"row justify-content-between\">\n<div class=\"col-12 col-lg-4 mb-5 mb-lg-0\">\n                      <img decoding=\"async\" src=\"https:\/\/yamate.clinic\/wp-content\/themes\/yycen\/assets\/img\/external-img\/nad-kit.jpg\" class=\"img-fluid\" alt=\"NAD+\"><\/div>\n<div class=\"col-12 col-lg-7\">\n<p class=\"mb-3\">\n                        NAD+ (nicotinamide adenine dinucleotide) is a key coenzyme found in all cells that supports mitochondrial function, which generates energy (ATP). This product aims to efficiently replenish NAD+ levels that decline with age, with the goal of improving brain function, promoting anti-aging, and restoring mitochondrial function.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"text-center\">\n                <a href=\"https:\/\/www.yamate.clinic\/en\/external\/nad-nasal-spray\/\" class=\"btn btn-primary\">View Details<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"row mb-5\">\n<div class=\"col-12 col-lg-6\">\n<div class=\"item-box mb-5 wow fadeInUp\" id=\"01\" data-wow-delay=\"0.1s\">\n<h3>Hydroquinone 4% Cream 5g Topical Medication<\/h3>\n<div class=\"py-2\">\n                <span class=\"item-2\">Dark Spots<\/span><span class=\"item-2\">Pigmentation<\/span><span class=\"item-2\">Melasma<\/span><span class=\"item-2\">Skin Whitening<\/span><\/div>\n<div class=\"card mb-3\">\n<div class=\"card-body\">\n<div class=\"row\">\n<div class=\"col-4\">\n                      <img decoding=\"async\" src=\"https:\/\/yamate.clinic\/wp-content\/themes\/yycen\/assets\/img\/external-img\/hydroquinone.jpg\" class=\"img-fluid\" alt=\"Hydroquinone\"><\/div>\n<div class=\"col-8\">\n<p class=\"mb-3\">Hydroquinone is an effective whitening ingredient that prevents the production of melanin, the cause of dark spots, thereby preventing their formation, and also promotes the elimination of existing dark spots. It is also known as a skin bleaching agent.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"text-center\">\n                <a href=\"\" data-bs-target=\"#m01\" data-bs-toggle=\"modal\" class=\"btn btn-primary\">View Details<\/a><\/div>\n<\/div>\n<\/div>\n<div class=\"col-12 col-lg-6\">\n<div class=\"item-box mb-5 wow fadeInUp\" id=\"02\" data-wow-delay=\"0.1s\">\n<h3>Azelaic Acid Cream AZA Clear<\/h3>\n<div class=\"py-2\">\n                <span class=\"item-2\">Acne<\/span><span class=\"item-2\">Acne Scars<\/span><span class=\"item-2\">Rosacea<\/span><\/div>\n<div class=\"card mb-3\">\n<div class=\"card-body\">\n<div class=\"row\">\n<div class=\"col-4\">\n                      <img decoding=\"async\" src=\"https:\/\/yamate.clinic\/wp-content\/themes\/yycen\/assets\/img\/external-img\/azelaic.jpg\" class=\"img-fluid\" alt=\"Azelaic Acid\"><\/div>\n<div class=\"col-8\">\n<p class=\"mb-3\">Azelaic acid has been used overseas for over 30 years as a safe acne treatment. It effectively prevents and improves acne by suppressing sebaceous gland activity and inhibiting abnormal keratinization.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"text-center\">\n                <a href=\"\" data-bs-target=\"#m02\" data-bs-toggle=\"modal\" class=\"btn btn-primary\">View Details<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<p>  <\/main><\/p>\n<p><!-- Modal 01--><\/p>\n<div class=\"modal-area\">\n<div class=\"modal fade\" id=\"m01\" tabindex=\"-1\" aria-labelledby=\u201c\u201d aria-hidden=\u201ctrue\u201d>\n<div class=\"modal-dialog modal-xl modal-dialog-centered\">\n<div class=\"modal-content\">\n<div class=\"modal-header bg-lightbeige pb-3\">\n<h1 class=\"modal-title fs-3\">Hydroquinone 4% Cream 5g Topical Medication<\/h1>\n<p><button type=\"button\" class=\"btn-close\" data-bs-dismiss=\"modal\" aria-label=\"Close\"><\/button><\/div>\n<div class=\"modal-body\">\n<div class=\"item-box\">\n<div class=\"py-2\">\n                <span class=\"item-2\">Dark Spots<\/span><span class=\"item-2\">Pigmentation<\/span><span class=\"item-2\">Melasma<\/span><span class=\"item-2\">Brightening Effect<\/span><\/div>\n<div class=\"card\">\n<div class=\"card-body\">\n<div class=\"row\">\n<div class=\"col-6 col-sm-3\">\n<div class=\"mb-4\">\n                        <img decoding=\"async\" src=\"https:\/\/yamate.clinic\/wp-content\/themes\/yycen\/assets\/img\/external-img\/hydroquinone.jpg\" class=\"img-fluid\" alt=\"Hydroquinone\"><\/div>\n<\/div>\n<div class=\"col-12 col-sm-9\">\n<div class=\"mb-5\">\n<h5>What Are the Effects of Hydroquinone Cream?<\/h5>\n<p class=\"mb-3\">Melanin pigment, produced by melanocytes that cause dark spots, is created to protect the skin when it is exposed to ultraviolet rays. Normally, it is exfoliated through skin turnover (skin metabolism). However, excessive UV exposure or disruption of the turnover cycle can lead to its excessive accumulation, causing dark spots.<\/p>\n<p class=\"mb-3\">This is how dark spots form. Hydroquinone is recognized for its ability to suppress melanocyte activity and inhibit melanin production.<br class=\"br\">Furthermore, it works by inhibiting the enzyme \u201ctyrosinase,\u201d which is involved in melanin production. Hydroquinone is also called a skin bleaching agent. Through this same mechanism, it can be expected to improve not only dark spots but also hyperpigmentation and melasma.<\/p>\n<\/div>\n<div class=\"mb-5\">\n<h5>Price<span class=\"font-14 ml-15\">(include tax)<\/span><\/h5>\n<div class=\"alert bg-light border mx-lg-4\">\n<div class=\"row justify-content-between align-items-center\">\n<div class=\"col-12 col-lg-7\">\n                              Hydroquinone 4% Cream 5<\/div>\n<div class=\"col-12 col-lg-3 text-end\">\n                              <span class=\"amount\">\u00a52,200<\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"mb-5\">\n<h5>Directions for Use<\/h5>\n<p>Apply an appropriate amount only to the necessary areas once daily at night after cleansing, on clean skin. (It can be applied as the final step in your usual skincare routine or after toner.)<\/p>\n<p>Store in the refrigerator. (The product may discolor to yellow or brown if quality deteriorates. Discontinue use if this occurs.)<br \/>\nUse continuously for 2 weeks to 3 months, followed by a 1-month break. Do not use continuously for more than 6 months.<\/p>\n<\/div>\n<div class=\"mb-5\">\n<h5>Recommended Together<\/h5>\n<p>Lumecca, Sylfirm X, Whitening Set, Tachyon Oral Medication, High-Concentration Vitamin C Drip, Whitening Drip<\/p>\n<\/div>\n<div class=\"5\">\n<h5>Precautions<\/h5>\n<ul class=\"fs-5 ps-3\">\n<li>Do not use if you are pregnant, breastfeeding, or planning to become pregnant.<\/li>\n<li>Avoid contact with mucous membranes and eyes.<\/li>\n<li>Not for use on children under 12 years old. Only the purchaser may use this product.<\/li>\n<li>Skin may become more sensitive during use; ensure adequate moisturization and UV protection.<\/li>\n<li>Redness or irritation may occur for about 2 weeks after starting use. Discontinue use if redness persists, if a rash develops, or if a strong stinging sensation occurs.<br \/>\n\u30fbIf peeling occurs, do not touch the area and moisturize.<br \/>\n\u30fbAlthough extremely rare, there is a potential risk of developing white patches.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"modal-footer\">\n            <button type=\"button\" class=\"btn btn-outline-secondary btn-sm\" data-bs-dismiss=\"modal\">Close<\/button><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"modal-area\">\n<div class=\"modal fade\" id=\"m02\" tabindex=\"-1\" aria-labelledby=\"\" aria-hidden=\"true\">\n<div class=\"modal-dialog modal-xl modal-dialog-centered\">\n<div class=\"modal-content\">\n<div class=\"modal-header bg-lightbeige pb-3\">\n<h1 class=\"modal-title fs-3\">Azelaic Acid Cream AZA Clear<\/h1>\n<p><button type=\"button\" class=\"btn-close\" data-bs-dismiss=\"modal\" aria-label=\"Close\"><\/button><\/div>\n<div class=\"modal-body\">\n<div class=\"item-box\">\n<div class=\"py-2\">\n                <span class=\"item-2\">Acne<\/span><span class=\"item-2\">Acne Scars<\/span><span class=\"item-2\">Redness<\/span><\/div>\n<div class=\"card\">\n<div class=\"card-body\">\n<div class=\"row\">\n<div class=\"col-6 col-sm-3\">\n<div class=\"mb-4\">\n                        <img decoding=\"async\" src=\"https:\/\/yamate.clinic\/wp-content\/themes\/yycen\/assets\/img\/external-img\/azelaic.jpg\" class=\"img-fluid\" alt=\"Azelaic Acid\"><\/div>\n<\/div>\n<div class=\"col-12 col-sm-9\">\n<div class=\"mb-5\">\n<h5>What is Azelaic Acid?<\/h5>\n<p>Azelaic acid has been used overseas for over 30 years as a safe acne treatment.<br \/>\nIt is a naturally derived ingredient found in grains like wheat and rye, effective for improving acne, clogged pores, dullness, and redness.<br \/>\nIt suppresses keratinization abnormalities (where old keratin builds up and forms comedones) that cause acne, and has antibacterial activity, anti-inflammatory effects, and inhibits sebum secretion and melanin production.<br \/>\nAzelainic acid is not only effective for acne treatment but also shows promise for reducing redness, dark spots, and brightening the skin. It can be used during pregnancy, breastfeeding, and by children under 12 years old, ensuring a higher level of safety.<br \/>\nA 15% or higher concentration of azelaic acid has proven efficacy. Compared to treatments using vitamin A, it has less irritation, making it easier to continue treatment.<\/p>\n<\/div>\n<div class=\"mb-5\">\n<h5>Details<\/h5>\n<p>The azelaic acid product available at our clinic is AZA Clear, a clinic-exclusive skincare cosmetic from Rohto Pharmaceutical. It is a 15g cream containing a high concentration of 20% azelaic acid.<\/p>\n<ul class=\"ps-3\">\n<li>Focuses on clogged pores, a cause of acne<\/li>\n<li>Home skincare for acne-prone skin<\/li>\n<li>Non-greasy, moisturizing feel<\/li>\n<li>Non-comedogenic tested<\/li>\n<li>Fragrance-free, colorant-free, preservative-free<\/li>\n<\/ul>\n<\/div>\n<div class=\"mb-5\">\n<h5>Price<span class=\"font-14 ml-15\">(include tax)<\/span><\/h5>\n<div class=\"alert bg-light border mx-lg-4\">\n<div class=\"row justify-content-between align-items-center\">\n<div class=\"col-12 col-lg-8\">\n                              20% High-Concentration Azelaic Acid Cream 15g<\/div>\n<div class=\"col-12 col-lg-2 text-end\">\n                              <span class=\"amount\">\u00a51,980<\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"mb-5\">\n<h5>How to Use<\/h5>\n<p>Apply as the final step in your morning and evening skincare routine. Can be used on specific areas or the entire face.<\/p>\n<p>For best results, we recommend continuous use for at least 2 months.<\/p>\n<p>Some users may experience a stinging sensation or redness during the first week or two of use. This is a normal reaction, so we ask that you monitor it. If the stinging or redness persists for more than 4 weeks or worsens, please come in for a consultation.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"modal-footer\">\n            <button type=\"button\" class=\"btn btn-outline-secondary btn-sm\" data-bs-dismiss=\"modal\">Close<\/button><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>External Medications Home External Medicine NAD+ Nasal Liposome Kit Cognitive FunctionFocusMemoryNeuroprotecti [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.yamate.clinic\/en\/wp-json\/wp\/v2\/pages\/1575"}],"collection":[{"href":"https:\/\/www.yamate.clinic\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.yamate.clinic\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.yamate.clinic\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.yamate.clinic\/en\/wp-json\/wp\/v2\/comments?post=1575"}],"version-history":[{"count":5,"href":"https:\/\/www.yamate.clinic\/en\/wp-json\/wp\/v2\/pages\/1575\/revisions"}],"predecessor-version":[{"id":2207,"href":"https:\/\/www.yamate.clinic\/en\/wp-json\/wp\/v2\/pages\/1575\/revisions\/2207"}],"wp:attachment":[{"href":"https:\/\/www.yamate.clinic\/en\/wp-json\/wp\/v2\/media?parent=1575"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}